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CALSCALE:GREGORIAN
METHOD:PUBLISH
BEGIN:VEVENT
UID:event-162401@localz.events
DTSTAMP:20261113T135612Z
LAST-MODIFIED:20261110T053115Z
DTSTART:20261113T084500Z
DTEND:20261113T094500Z
SUMMARY:CAM Colloquium - November 13\, 2026\, April Wei "The ancestral reco
 mbination graph: latent structure for compression and inference in populat
 ion genetics"
DESCRIPTION:Title: The ancestral recombination graph: latent structure for 
 compression and inference in population genetics Abstract: The genomes wit
 hin a species are related through an ancestral recombination graph (ARG)\,
  a sequence of genealogical trees along the genome that encodes the coales
 cence and recombination history of the samples. While genome sequences can
  now be observed directly\, the ARG remains the latent object that is diff
 icult to infer. Yet\, it underlies most questions in population genetics\,
  and its structure can be exploited both to compress the genotype data and
  to compute data likelihoods. I will describe two lines of work from my gr
 oup. The first is the development of the genotype representation graph (GR
 G)\, a simpler ARG-like graph that encodes shared haplotype structure amon
 g samples. The GRG is a lossless encoding of the genotype matrix\, equival
 ent to a factorization of the matrix into sparse factors\, so that a matri
 x-vector product can be computed by a single graph…\n\nhttps://localz.ev
 ents/e/cam-colloquium-november-13-2026-april-wei-the-ancestral-recombinati
 on-graph-latent-structure-for-compression-and-inference-in-population-gene
 tics-162401
LOCATION:Frank H. T. Rhodes Hall\, Ithaca
GEO:42.443451;-76.481506
URL:https://localz.events/e/cam-colloquium-november-13-2026-april-wei-the-a
 ncestral-recombination-graph-latent-structure-for-compression-and-inferenc
 e-in-population-genetics-162401
STATUS:CONFIRMED
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