Challenge Walk MS - St. Louis

Challenge Walk MS: St. Louis is a 2-day 50k walking event that will take you farther than you’ve gone before. Walk both days or just one. Participate virtually or as a volunteer. Choose your own challenge!

Every year, Challenge Walk MS: St. Louis brings together some of the most dedicated family members, friends, and strangers to walk 50k closer to a cure for MS. This special Challenge Walk “family” vows to put one foot in front of the other on behalf of those who can’t…until they can.

Your participation will drive MS research forward faster, and deliver services to those who face the challenges of MS everyday so they can live their best lives.

Are you up for the Challenge?

Join us as we celebrate our 17th year in the St. Louis area! This year, we're excited to announce we'll be calling Fontbonne University "home" for the weekend!

You can choose to participate one or both days. Your fundraising requirement is based on how many days you participate:
Challenge Walker - 1 Day = $500
Challenge Walker - 2 Days = $1,000
Virtual Walker = free
Volutneer = free

Online registration is up and running at! Register today, for the lowest registration fee between now and the event.

This is a fully-supported event for all Challenge Walkers. Overnight accommodations are available Friday and Saturday, June 1-2.

If you have questions, please contact event lead Meghan Freeman at or 314-446-4165.
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